Ontogenetic Study on Allorectivity in the Chicken: Analysis by Graft Versus Host Reaction and Mixed Lymphocyte Reaction.
نویسندگان
چکیده
منابع مشابه
Cytotoxicity in Graft-versus-host Reaction
Under in vitro conditions spleen cells from nonirradiated F(1) hybrids, in which a (graft-vs.-host) (GVH) reaction had been induced with lymphoid cells of parental origin, lysed nonspecifically target cells, i.e., cells syngeneic or allogeneic to the parental genotypes. Furthermore, tumor cells exposed in vitro to spleen cells of F(1) hybrid mice undergoing GVH reaction had markedly decreased a...
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Spleen organ cultures were prepared from lethally irradiated mice that had been injected with allogeneic bone marrow, with or without lymph node cells. These cultures were used in the analysis of graft-versus-host reactions (GVHR) in vitro. It was found that donor-derived T lymphocytes, which had been grown in an allogeneic spleen, prevented hemopoietic progenitor cells (colony-forming cells, C...
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A graft-versus-host reaction was induced in (BALB/c x C5 7BL/6)F(1) mice by intravenous injection of BALB/c spleen cells. Six days later, the mice received subcutaneous grafts of a chemically induced BALB/c sarcoma. The growth of the tumor grafts was accelerated.
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Allogeneic immunocompetent T cells injected into chicken embryos induce a graft-versus-host reaction (GVHR) whose most prominent manifestation is splenic hyperplasia. The highly inbred CC and CB strains of chickens used here are, respectively, homozygous for the B4 or B12 MHC haplotypes. By means of a panel of immunological reagents, including alloantisera and monoclonal antibodies against publ...
متن کاملSelective viral immunosuppression of the graft-versus-host reaction
Graft-vs.-host (GVH) reactivity of parental lymph node (LN) cells was assayed by measurements of 3H-thymidine incorporation in vivo in spleens of irradiated F1 recipients. Preincubation of parental LN cells with vesicular stomatitis virus (VSV) for 2 h at 37 degrees C followed by washing resulted in an 85-90% reduction in splenic radioactivity, as did injection of VSV on days 0-2 after recipien...
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ژورنال
عنوان ژورنال: Japanese poultry science
سال: 1994
ISSN: 0029-0254
DOI: 10.2141/jpsa.31.9